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CSF changes during acute meningoencephalitis in mice caused by encephalomyocarditis virus
Author(s) -
Griffin Diane E.
Publication year - 1981
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410100111
Subject(s) - meningoencephalitis , virology , virus , medicine , cerebrospinal fluid , immunology , pathology
Encephalomyelitis was induced in mice by intravenous inoculation with encephalomyocarditis virus. Examination of the cerebrospinal fluid revealed marked pleocytosis and increased amounts of protein, including immunoglobulins. These proteins entered the cerebrospinal fluid by transfer from serum during the period of central nervous system infection.