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Altered muscle polyamine levels in human neuromuscular diseases
Author(s) -
Kaminska Anna M.,
Stern Lawrence Z.,
Russell Diane Haddock
Publication year - 1981
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410090615
Subject(s) - polyamine , intracellular , neuromuscular disease , human muscle , medicine , endocrinology , biology , disease , chemistry , microbiology and biotechnology , biochemistry , skeletal muscle
Intracellular polyamine levels were measured in 17 patients with neuromuscular diseases and 13 normal controls and were correlated with morphological changes in muscle biopsies. Elevated polyamine levels were found in muscles with marked morphological changes, regardless of the nature of the disease process.