Premium
Cerebral hemodynamics and metabolism in postoperative cerebral vasospasm and treatment with hypertensive therapy
Author(s) -
Montgomery Erwin B.,
Grubb Robert L.,
Raichle Marcus E.
Publication year - 1981
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410090514
Subject(s) - medicine , subarachnoid hemorrhage , cerebral blood flow , vasospasm , anesthesia , clipping (morphology) , cerebral vasospasm , aneurysm , internal carotid artery , hemodynamics , blood pressure , cardiology , surgery , philosophy , linguistics
A 24‐year‐old woman developed subarachnoid hemorrhage from an aneurysm at the bifurcation of the right internal carotid artery. Following successful clipping of the aneurysm she developed a left hemiplegia associated with focal cerebral vasospasm, which markedly improved when systemic blood flow and oxygen utilization were significantly depressed in both cerebral hemispheres, while blood volume was significantly elevated only on the side with vasospasm. Oxygen extraction was significantly elevated in both hemispheres, indicating a generalized impairment in oxygen delivery to the brain.