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Demyelination of the lateral geniculate nucleus in central pontine myelinolysis
Author(s) -
Goldman James E.,
Horoupian Dikran S.
Publication year - 1981
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410090213
Subject(s) - lateral geniculate nucleus , central pontine myelinolysis , geniculate body , geniculate , neuroscience , central nervous system , nucleus , pathology , myelin , pons , pathological , anatomy , medicine , biology , magnetic resonance imaging , retina , visual cortex , radiology
Postmortem examination of the central nervous system in 6 of 9 patients with central pontine myelinolysis (CPM) revealed demyelination in the lateral geniculate nucleus (LGN). Histologically, the geniculate lesions consisted of myelin swelling and disintegration, largely in the central part of the nucleus, with preservation of axons and neuronal perikarya. The pathological changes resembled those found in the basis pontis in CPM.