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Sodium valproate and bone marrow suppression
Author(s) -
Smith F. R.,
Boots M.
Publication year - 1980
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410080213
Subject(s) - bone marrow , medicine , coagulopathy , valproic acid , bone marrow suppression , regimen , platelet , mood stabilizer , chemotherapy , bipolar disorder , epilepsy , psychiatry , lithium (medication)
Bone marrow suppression developed in a patient while she was on a regimen of sodium valproate. In addition, she had high titers of platelet autoantibodies and a coagulopathy, both recognized complications of valproate therapy. It is postulated that this drug was also responsible for the marrow suppression.