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Basal lamina formation at the site of spinal cord transection
Author(s) -
Feringa Earl R.,
Kowalski Timothy F.,
Lee Vahlsing H.
Publication year - 1980
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410080204
Subject(s) - spinal cord , basal lamina , anatomy , central nervous system , spinal cord injury , lamina , lesion , immunohistochemistry , pathology , neuroglia , medicine , biology , neuroscience , ultrastructure
The pia‐glial basal lamina (BL) at the site of spinal cord injury could be an important physical impediment to central nervous system regeneration. We used an epithelial BL‐specific immunohistochemical stain to determine the location of the pia‐glial BL after spinal cord transection. Small segments of BL were found at the margin of the lesion 5 days after transection. After 10 days, longer and more numerous segments were seen. At 20 days, the entire transected end of the spinal cord was capped by a layer of BL.