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Familial stroke syndrome associated with mitral valve prolapse
Author(s) -
Rice G. P. A.,
Boughner D. R.,
Stiller C.,
Ebers G. C.
Publication year - 1980
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410070207
Subject(s) - mitral valve prolapse , medicine , stroke (engine) , cardiology , mitral valve , physical medicine and rehabilitation , mechanical engineering , engineering
In a 27‐member family, 8 individuals had mitral valve prolapse (MVP) by echocardiography. Four of them suffered a total of eight cerebral ischemic events in the first four decades of life. In none of these patients could risk factors for stroke, other than MVP, be found. Stroke did not occur in individuals free of MVP. This report draws attention to a previously unrecognized cause of familial stroke which strengthens the relationship between MVP and premature stroke.