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Cytoarchitectonic abnormalities in developmental dyslexia: A case study
Author(s) -
Galaburda Albert M.,
Kemper Thomas L.
Publication year - 1979
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410060203
Subject(s) - dyslexia , developmental dyslexia , polymicrogyria , lateralization of brain function , psychology , reading (process) , cerebral hemisphere , right hemisphere , limbic system , neuroscience , association (psychology) , cytoarchitecture , audiology , medicine , cognitive psychology , central nervous system , epilepsy , political science , law , psychotherapist
A patient is reported who had a well‐documented history of developmental dyslexia. Reading difficulties were present in other male members of the immediate family. Gross anatomical and cytoarchitectonic analysis of the brain in serial sections showed a consistently wider left cerebral hemisphere, an area of polymicrogyria in the left temporal speech region, and mild cortical dysplasias in limbic, primary, and association cortices of the left hemisphere.