Premium
Failure of chronic dorsal column stimulation in multiple sclerosis
Author(s) -
Rosen James A.,
Barsoum Adib H.
Publication year - 1979
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410060115
Subject(s) - multiple sclerosis , ambulatory , placebo , stimulation , dorsum , medicine , open label , physical medicine and rehabilitation , column (typography) , physical therapy , anesthesia , surgery , randomized controlled trial , pathology , psychiatry , anatomy , alternative medicine , computer science , telecommunications , frame (networking)
Abstract In view of the favorable claims of Cook and others, an open trial of chronic dorsal column stimulation was undertaken in 9 patients who had moderately advanced multiple sclerosis (MS) but were still ambulatory. No objective improvement was noted by either author during the postoperative observation period of 6 to 37 months; the occasional subjective improvement was ascribed to placebo effect. This procedure can no longer be recommended for MS patients.