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The aicardi syndrome: Report of 4 cases and review of the literature
Author(s) -
Bertoni John M.,
von Loh Siegrun,
Allen Richard J.
Publication year - 1979
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410050513
Subject(s) - agenesis of the corpus callosum , corpus callosum , medicine , corpus callosum agenesis , agenesis , pediatrics , epilepsy , pathology , anatomy , psychiatry
The findings in 4 cases of Aicardi syndrome (female infants with mental retardation, seizures, characteristic eye lesions, agenesis of the corpus callosum, vertebral anomalies, and abnormal but nondiagnostic electroencephalographic patterns) are compared to 39 previously reported cases. Available information suggests tha the syndrome results from an unknown intrauterine insult occurring no later than the first trimester. No familial cases have been reported, and the cause remains unknown.