Premium
Fatal long‐term sequela following radiation “cure” for ependymoma
Author(s) -
Bachman David S.,
Ostrow Peter T.
Publication year - 1978
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410040406
Subject(s) - ependymoma , sequela , medicine , radiation therapy , lesion , pathological , encephalopathy , central nervous system , glioblastoma , central nervous system disease , surgery , pathology , cancer research
There are no previous reports of glioblastoma occurring following central nervous system irradiation. This report describes a young girl with an ependymoma at age 13 months who was treated by radiotherapy following surgical removal. At age 6 years she presented with a new lesion in the same location. Histologically there was no evidence of recurrent ependymoma. Instead, the pathological picture suggested glioblastoma or a severe radiation‐induced encephalopathy. In either case, it seems likely that the changes were radiation induced.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom