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Cerebral hypoperfusion in the sudden infant death syndrome? brainstem gliosis and vasculature
Author(s) -
Takashima S.,
Armstrong D.,
Becker L.,
Bryan C.
Publication year - 1978
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410040312
Subject(s) - gliosis , brainstem , medicine , sudden infant death syndrome , hypoxia (environmental) , perfusion , cerebral hypoperfusion , pathology , ischemia , sudden death , cardiology , neuroscience , pediatrics , psychology , chemistry , organic chemistry , oxygen
Gliosis is increased in the respiratory control area of the brainstem in victims of sudden infant death syndrome (SIDS), as it is in infants who have died of congenital heart disease. In the latter, the lesions appear to result from hypoxia or ischemia, and studies of the brainstem microvasculature of SIDS victims indicated a close relationship between the gliosis and adjacent vasculature. It is postulated that cerebral hypoperfusion may play a role in SIDS.