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Alteration in erythrocyte membrane structure in duchenne muscular dystrophy
Author(s) -
Wakayama Y.,
Hodson A.,
Pleasure D.,
Bonilla E.,
Schotland D. L.
Publication year - 1978
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410040311
Subject(s) - duchenne muscular dystrophy , erythrocyte membrane , abnormality , membrane , muscular dystrophy , medicine , chemistry , biochemistry , psychiatry
Abstract Freeze‐fracture studies of erythrocytes from patients with Duchenne muscular dystrophy revealed depletion of particles on both fracture faces of the plasma membrane. This study indicates that the structure of the erythrocyte plasma membrane is abnormal in Duchenne dystrophy and supports the concept that a generalized membrane abnormality is present in this disease.