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Ependymal changes in the human fetal brain
Author(s) -
Dooling Elizabeth C.,
Chi Je G.,
Gilles Floyd H.
Publication year - 1977
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410010605
Subject(s) - ependymal cell , lateral ventricles , gliosis , corpus callosum , anatomy , ependyma , fetus , subependymal zone , biology , hippocampus , pathology , neuroscience , central nervous system , medicine , pregnancy , genetics
Focal ependymal loss, increasing in extent with advancing gestational age, was found in 111 human fetal brains. Its regular occurrence in specific sites, viz, the lateral walls of the lateral ventricles, over sector CA 2 of the hippocampus, and on the ventral surface of the corpus callosum and lateral walls of the septum pellucidum, without prominent subependymal gliosis, suggests that restricted ependymal loss may be related to growth and development of the fetal brain. More extensive loss should be considered a marker of a neuropathological process.