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Comparison of ribosomal subunit proteins from normal human and Huntington's disease skin fibroblasts
Author(s) -
Prashad Nagindra,
Rosenberg Roger N.
Publication year - 1977
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410010512
Subject(s) - protein subunit , polyacrylamide gel electrophoresis , puromycin , ribosomal rna , ribosomal protein , gel electrophoresis , microbiology and biotechnology , sodium dodecyl sulfate , biology , huntington's disease , chemistry , biochemistry , disease , medicine , pathology , ribosome , protein biosynthesis , enzyme , rna , gene
The ribosomal subunit proteins from skin fibroblasts of normal persons and patients with Huntington's disease (HD) were isolated by KCI‐puromycin and by EDTA treatments and were compared by sodium dodecyl sulfate polyacrylamide gel electrophoresis. The data indicate that the ribosomal proteins are identical in control and HD fibroblasts.