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Isolated myopathic involvement of the diaphragmatic musculature in a neonate
Author(s) -
Bergen Barry J.,
Sangalang Virgilio E.,
Aterman Kurt
Publication year - 1977
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410010414
Subject(s) - diaphragmatic breathing , medicine , neuroscience , pathology , anatomy , psychology , alternative medicine
A myopathy restricted to the diaphragm was found in an infant who died at 3 months of age of respiratory failure due immobility of the diaphragm. Grossly, the diaphragm was thin and translucent. On microscopical examination few muscle bundles were seen. Most muscle fibers were small, and numerous necrotic fibers with large sarcolemmal nuclei, focal cytoplasmic basophilia, and hyaline or homogeneous eosinophilic degeneration in the center of the fibers were seen.