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Whipple's disease with predominantly neuroophthalmic manifestations
Author(s) -
Finelli Pasquale F.,
McEntee William J.,
Lessell Simmons,
Morgan Thomas F.,
Copetto James
Publication year - 1977
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410010308
Subject(s) - whipple's disease , whipple disease , medicine , disease , gaze , uveitis , dementia , paralysis , tropheryma whipplei , pathology , surgery , psychology , ophthalmology , psychoanalysis , coeliac disease , intestinal malabsorption
Supranuclear paralysis of gaze was a prominent manifestation of Whipple's disease in 2 patients with dementia, 1 of whom also had bilateral uveitis. Because of the absence of gastrointestinal problems in these patients, correct diagnosis was delayed. Whipple's disease is a treatable disorder and should be considered in patients with otherwise unexplained supranuclear gaze paralysis and uveitis.