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The effect of isoprinosine in subacute sclerosing panencephalitis (SSPE)
Author(s) -
Streletz L. J.,
Cracco J.
Publication year - 1977
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410010214
Subject(s) - subacute sclerosing panencephalitis , medicine , natural history , virology , measles , measles virus , vaccination
Although no therapeutic agent has proved to be of benefit in subacute sclerosing panencephalitis (SSPE), the use of Isoprinosine has been associated with clinical improvement in several preliminary reports. Two additional patients with SSPE are presented who had repeated serological and electroencephalographic studies during therapy with Isoprinosine. Their clinical courses are discussed in view of the laboratory findings and the natural history of the disease.