Premium
Annals of Neurology: Volume 86, Number 6, December 2019
Publication year - 2019
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.25626
Subject(s) - glymphatic system , clearance , schematic , annals , medicine , blood flow , lymphatic system , perivascular space , anatomy , nuclear medicine , pathology , cardiology , cerebrospinal fluid , art , classics , urology , electronic engineering , engineering
A schematic diagram of the glymphatic flow pathway and its alteration by focused ultrasound that opens the blood‐brain barrier. In the lower part of the figure, gadolinium (small black particles) in the red arterial blood enters the brain and flows through into blue veins. Focused ultrasound (green waves in the upper part of the figure) allows particles to enter the interstitial space where they are carried by bulk flow into perivenular spaces and from which they are cleared by meningeal lymphatic vessels (green). Illustration by Hang Yu Lin. See Meng et al. on pp. 975–980 , in this issue for details.