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High‐resolution diffusion‐weighted imaging identifies ischemic lesions in a majority of transient ischemic attack patients
Author(s) -
Hotter Benjamin,
Galinovic Ivana,
Kunze Claudia,
Brunecker Peter,
Jungehulsing Gerhard J.,
Villringer Arno,
Endres Matthias,
Villringer Kersten,
Fiebach Jochen B.
Publication year - 2019
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.25551
Subject(s) - medicine , magnetic resonance imaging , ischemia , diffusion mri , ischemic stroke , stroke (engine) , brain ischemia , cohort , radiology , neuroimaging , perfusion , cardiology , psychiatry , mechanical engineering , engineering
Transient ischemic attack (TIA) is defined as focal neurological deficit caused by ischemia resolving within 24 hours. In a secondary analysis of a large monocentric cohort of 446 TIA patients, we explored the frequency and determinants of diffusion‐weighted imaging (DWI) lesions on high‐resolution magnetic resonance imaging. Overall, 240 (54%) of all TIA patients presented with DWI lesions. These patients had higher National Institute of Health Stroke Scale and ABCD2 scores and presented more frequently with vessel occlusion and perfusion deficits, but had similar functional outcome at 3 months. Taken together, high‐resolution DWI provides evidence of ischemic brain injury in the majority of TIA patients. ANN NEUROL 2019;86:452–457