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Flow diversion for treatment of intracranial aneurysms: Mechanism and implications
Author(s) -
Chua Melissa M. J.,
Silveira Luke,
Moore Justin,
Pereira Vitor M.,
Thomas Ajith J.,
Dmytriw Adam A.
Publication year - 2019
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.25484
Subject(s) - flow diverter , aneurysm , medicine , flow (mathematics) , mechanism (biology) , blood flow , occlusion , radiology , cardiology , mechanics , physics , quantum mechanics
Flow diverters are new generation stents that have recently garnered a large amount of interest for use in treatment of intracranial aneurysms. Flow diverters reduce blood flow into the aneurysm, with redirection along the path of the parent vessel. Flow stagnation into the aneurysm and neck coverage with subsequent endothelialization are the important synergistic mechanisms by which the therapy acts. Several studies have examined the mechanisms by which flow diverters subsequently lead to aneurysm occlusion. This review aims to provide a general overview of the flow diverters and their mechanism of action and potential implications. ANN NEUROL 2019;85:793–800.