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Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis
Author(s) -
BandresCiga Sara,
Noyce Alastair J.,
Hemani Gibran,
Nicolas Aude,
Calvo Andrea,
Mora Gabriele,
Tienari Pentti J.,
Stone David J.,
Nalls Mike A.,
Singleton Andrew B.,
Chiò Adriano,
Traynor Bryan J.
Publication year - 2019
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.25431
Subject(s) - mendelian randomization , genome wide association study , linkage disequilibrium , causal inference , causality (physics) , multifactorial inheritance , psychology , clinical psychology , medicine , genetics , biology , allele , genetic variants , haplotype , single nucleotide polymorphism , genotype , pathology , quantum mechanics , gene , physics
To identify shared polygenic risk and causal associations in amyotrophic lateral sclerosis (ALS).