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Visual processing in migraineurs depends on the migraine cycle
Author(s) -
Luedtke Kerstin,
Schulte Laura H.,
May Arne
Publication year - 2019
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.25398
Subject(s) - ictal , migraine , excitatory postsynaptic potential , inhibitory postsynaptic potential , visual cortex , duration (music) , medicine , anesthesia , neuroscience , audiology , epilepsy , psychology , physics , acoustics
We investigated changes of after‐image duration in migraineurs and healthy controls (HCs) and throughout the migraine cycle to depict changes in the excitatory/inhibitory equilibrium within the visual cortex. Forty‐seven episodic (EMs) and 39 chronic migraineurs (CMs; interictal) were compared to 34 HCs for visual after‐image duration. Additionally, seven EMs were investigated every consecutive day over 20 to 32 days using the identical paradigm throughout the migraine cycle. Interictally, the after‐image duration was shorter compared to HCs, but significantly longer in the ictal compared to interictal phase. These data suggest an altered excitatory/inhibitory equilibrium in migraineurs, which oscillates over the migraine cycle. ANN NEUROL 2019;85:280–283.