Premium
Lyme Neuroborreliosis: Clinical Outcomes, Controversy, Pathogenesis, and Polymicrobial Infections
Author(s) -
GarciaMonco Juan Carlos,
Benach Jorge L.
Publication year - 2019
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.25389
Subject(s) - lyme neuroborreliosis , neuroborreliosis , lyme disease , medicine , borrelia , context (archaeology) , meningitis , pathogenesis , intensive care medicine , dermatology , borrelia burgdorferi , immunology , pediatrics , biology , paleontology , antibody
Lyme borreliosis is the object of numerous misconceptions. In this review, we revisit the fundamental manifestations of neuroborreliosis (meningitis, cranial neuritis, and radiculoneuritis), as these have withstood the test of time. We also discuss other manifestations that are less frequent. Stroke, as a manifestation of Lyme neuroborreliosis, is considered in the context of other infections. The summary of the literature regarding clinical outcomes of neuroborreliosis leads to its controversies. We also include new information on pathogenesis and on the polymicrobial nature of tick‐borne diseases. In this way, we update the review that we wrote in this journal in 1995. ANN NEUROL 2019;85:21–31.