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Reconstruction magnetic resonance neurography in chronic inflammatory demyelinating polyneuropathy
Author(s) -
Shibuya Kazumoto,
Sugiyama Atsuhiko,
Ito Shoichi,
Misawa Sonoko,
Sekiguchi Yukari,
Mitsuma Satsuki,
Iwai Yuta,
Watanabe Keisuke,
Shimada Hitoshi,
Kawaguchi Hiroshi,
Suhara Tetsuya,
Yokota Hajime,
Matsumoto Hiroshi,
Kuwabara Satoshi
Publication year - 2015
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.24314
Subject(s) - chronic inflammatory demyelinating polyneuropathy , magnetic resonance neurography , medicine , muscle hypertrophy , magnetic resonance imaging , polyneuropathy , pathophysiology , nerve root , pathology , anatomy , radiology , antibody , immunology
To study distribution and patterns of nerve hypertrophy in chronic inflammatory demyelinating polyneuropathy (CIDP), magnetic resonance neurography with 3‐dimensional reconstruction of short tau inversion recovery images was performed in 33 patients. This technique clearly showed longitudinal morphological changes from the cervical roots to the nerve trunks in the proximal arm. Nerve enlargement was detected in 88% of the patients. According to the clinical subtype of CIDP, typical CIDP patients showed symmetric and root‐dominant hypertrophy, whereas Lewis–Sumner syndrome patients had multifocal fusiform hypertrophy in the nerve trunks. The patterns of nerve hypertrophy presumably reflect the different pathophysiology of each CIDP subtype. Ann Neurol 2014.