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Isolated horizontal positional nystagmus from a posterior fossa lesion
Author(s) -
Lee HyoJeong,
Kim Eun Soo,
Kim Minbum,
Chu Hosuk,
Ma HyeoIl,
Lee Joong Seob,
Koo JaWon,
Kim HyungJong,
Hong Sung Kwang
Publication year - 2014
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.24292
Subject(s) - nystagmus , lesion , vertigo , cerebellar vermis , medicine , anatomy , joubert syndrome , cerebellum , audiology , pathology , surgery , biology , cilium , microbiology and biotechnology
Isolated vertigo with horizontal positional nystagmus as an impending sign of a central lesion has rarely been reported. Here we present neuro‐otologic findings of patients with these clinical signs. Lesion overlays from 6 patients with ageotropic positional nystagmus revealed that the nodulus and vermis are common areas of injury. In contrast, 2 patients with geotropic positional nystagmus had cerebellar peduncle and lateral medullary lesions. These clinical findings suggest that vertigo with horizontal positional nystagmus, even in the absence of other initial neurological signs, may indicate a posterior fossa lesion, including that in the nodulus, vermis, and deep cerebellar structures. Ann Neurol 2014;76:905–910