Premium
Ictal very low frequency oscillation in human epilepsy patients
Author(s) -
Ren Liankun,
Terada Kiyohito,
Baba Koichi,
Usui Naotaka,
Umeoka Shuichi,
Usui Keiko,
Matsuda Kazumi,
Tottori Takayasu,
Nakamura Fumihiro,
Mihara Tadahiro,
Inoue Yushi
Publication year - 2011
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.22158
Subject(s) - epileptogenesis , ictal , epilepsy , electroencephalography , psychology , neuroscience , medicine , audiology
Using intracranial electroencephalographic recordings, we identified a distinct brain activity in 3 patients with refractory epilepsy characterized by very early occurrence from 8 minutes 10 seconds to 22 minutes 40 seconds prior to clinical seizure onset, periodical appearance of slow negative baseline shift, long interpeak interval of 40 to 120 seconds, and disappearance after clinical seizure. We named this activity “very low frequency oscillation” (VLFO), which reflected a dynamic process during the preictal state. This observation may render new insight into epileptogenesis and provide additional information concerning the epileptogenic zone as well as prediction of epileptic seizures. Ann Neurol 2010