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Prognostic value of initial magnetic resonance imaging growth rates for World Health Organization grade II gliomas
Author(s) -
Pallud Johan,
Mandonnet Emmanuel,
Duffau Hugues,
Kujas Michèle,
Guillevin Rémy,
Galanaud Damien,
Taillandier Luc,
Capelle Laurent
Publication year - 2006
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.20946
Subject(s) - magnetic resonance imaging , medicine , glioma , survival rate , radiology , nuclear medicine , cancer research
A consecutive series of 143 unselected adult patients with histologically proved World Health Organization grade II gliomas was reviewed to assess the prognostic value of growth rates of mean tumor diameters on successive magnetic resonance images before treatment. There is an inverse correlation between growth rates and survival ( p < 0.001; median survival at 5.16 years for a growth rate of 8mm/year or more; median survival >15.0 years for a growth rate <8mm/year). Thus, individual magnetic resonance imaging tumor growth rates should be incorporated in the planning of the initial therapeutic strategy of grade II gliomas. Ann Neurol 2006;60:380–383