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Mobile phone emissions and human brain excitability
Author(s) -
Ferreri Florinda,
Curcio Giuseppe,
Pasqualetti Patrizio,
De Gennaro Luigi,
Fini Rita,
Rossini Paolo Maria
Publication year - 2006
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.20906
Subject(s) - transcranial magnetic stimulation , facilitation , lateralization of brain function , psychology , neuroscience , audiology , stimulation , medicine
Objective To test—via Transcranial Magnetic Stimulation (TMS)—the excitability of each brain hemisphere after ‘real’ or ‘sham’ exposure to the electromagnetic field (EMF) generated by a mobile phone operating in the Global System for Mobile Communication (GSM). Methods Fifteen male volunteers attended two experimental sessions, one week apart, in a cross‐over, double‐blind paradigm. In one session the signal was turned ON (EMF‐on, real exposure), in the other it was turned OFF (EMF‐off, sham exposure), for 45 minutes. Motor Evoked Potentials (MEPs) were recorded using a paired‐pulse paradigm (testing intracortical excitability with 1 to 17 ms interstimulus intervals), both before and at different times after exposure to the EMF. Short Intracortical Inhibition (SICI) and Facilitation (ICF) curves were evaluated both on the exposed and non‐exposed hemispheres. Tympanic temperature was collected during each session. Results The intracortical excitability curve becomes significantly modified during real exposure, with SICI being reduced and ICF enhanced in the acutely exposed brain hemisphere as compared to the contralateral, non‐exposed hemisphere or to sham exposure. Tympanic temperature showed no significant main effect or interactions. Interpretation These results demonstrate that GSM‐EMFs modify brain excitability. Possible implications and applications are discussed. Ann Neurol 2006