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A life course approach to cognitive reserve: A model for cognitive aging and development?
Author(s) -
Richards Marcus,
Deary Ian J.
Publication year - 2005
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.20637
Subject(s) - cognitive reserve , neuropathology , context (archaeology) , psychology , cognition , neuroscience , brain aging , cognitive aging , cognitive psychology , cognitive science , cognitive impairment , medicine , disease , pathology , biology , paleontology
The concept of reserve in neuroscience maintains that there are aspects of brain structure and function that can buffer the effects of neuropathology such that the greater the reserve, the more severe the pathology must be to cause functional impairment. This article provides a concise overview of structural and functional approaches to reserve and shows how reserve may be conceived as the sum of its lifetime input. In this context, reserve therefore provides an empirical yet general model of cognitive aging and development. Ann Neurol 2005;58:617–622