Premium
Torsin A haplotype predisposes to idiopathic dystonia
Author(s) -
Clarimon Jordi,
Asgeirsson Hilmir,
Singleton Andrew,
Jakobsson Finnbogi,
Hjaltason Haukur,
Hardy John,
Sveinbjornsdottir Sigurlaug
Publication year - 2005
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.20485
Subject(s) - dystonia , haplotype , medicine , neuroscience , physical medicine and rehabilitation , psychology , genetics , psychiatry , biology , allele , gene
Previous work has suggested that in many neurological diseases genetic variability in the loci predisposing subjects to autosomal dominant disease contributes to the risk of sporadic disease. Here, using a population‐based sample of dystonia cases, we show an association with the torsin A haplotype and sporadic idiopathic dystonia. Ann Neurol 2005;57:765–767