Molecular epidemiology of spinocerebellar ataxia type 6 | Zendy

Craig Kate | Zendy; Keers Sharon M. | Zendy; Archibald Kate | Zendy; Curtis Ann | Zendy; Chinnery Patrick F. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Molecular epidemiology of spinocerebellar ataxia type 6

Author(s) -

Craig Kate,

Keers Sharon M.,

Archibald Kate,

Curtis Ann,

Chinnery Patrick F.

Publication year - 2004

Publication title -

annals of neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.764

H-Index - 296

eISSN - 1531-8249

pISSN - 0364-5134

DOI - 10.1002/ana.20110

Subject(s) - confidence interval , epidemiology , spinocerebellar ataxia , population , ataxia , microsatellite , medicine , genetics , biology , gene , psychiatry , allele , environmental health

We performed a population‐based clinical and molecular genetic study of spinocerebellar ataxia type 6 (SCA6) in the northeast of England. The minimum point prevalence of SCA6 was 1.59 in 100,000 (95% confidence interval [CI], 1.04–2.14), and the number of individuals who either had SCA6 or are at risk of developing SCA6 was at least 5.21 in 100,000 (95% CI, 4.31–6.10), or 1 in 19,210. Microsatellite analysis of the CACNA1A gene indicated a founder effect for SCA6 within this region.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research