Premium
Adult‐onset leukoencephalopathy with vanishing white matter presenting with dementia
Author(s) -
Prass Konstantin,
Brück Wolfgang,
Schröder Nicolas W. J.,
Bender Andreas,
Prass Maria,
Wolf Tilo,
Van Der Knaap Marjo S.,
Zschenderlein Rolf
Publication year - 2001
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.1259
Subject(s) - leukoencephalopathy , white matter , dementia , magnetic resonance imaging , medicine , hyperintensity , pediatrics , pathology , radiology , disease
We report on a case of dementia and extensive cerebral white matter abnormalities seen on magnetic resonance images which meet the criteria for leukoencephalopathy with vanishing white matter. This is an inherited condition that was first thought to occur only in children. Our patient shows that vanishing white matter should be considered in adult patients with early‐onset dementia and extensive white matter changes seen on magnetic resonance images.