Dually infected (HSV‐1/VZV) single neurons in human trigeminal ganglia | Zendy

Theil Diethilde | Zendy; Paripovic Igor | Zendy; Derfuss Tobias | Zendy; Herberger Simone | Zendy; Strupp Michael | Zendy; Arbusow Viktor | Zendy; Brandt Thomas | Zendy

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Dually infected (HSV‐1/VZV) single neurons in human trigeminal ganglia

Author(s) -

Theil Diethilde,

Paripovic Igor,

Derfuss Tobias,

Herberger Simone,

Strupp Michael,

Arbusow Viktor,

Brandt Thomas

Publication year - 2003

Publication title -

annals of neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.764

H-Index - 296

eISSN - 1531-8249

pISSN - 0364-5134

DOI - 10.1002/ana.10746

Subject(s) - herpes simplex virus , varicella zoster virus , virology , latency (audio) , alphaherpesvirinae , biology , virus , trigeminal ganglion , hsl and hsv , herpesviridae , trigeminal nerve , in situ hybridization , neuroscience , anatomy , viral disease , genetics , gene , computer science , gene expression , telecommunications , sensory system

Human trigeminal ganglia were tested by double fluorescence in situ hybridization for the presence and distribution of herpes simplex virus type 1 (HSV‐1) and varicella‐zoster virus (VZV) latency. Latency transcripts of both viruses were detected in common areas within the ganglia. Also, a few single neurons were shown to harbor HSV‐1 and VZV together. Ann Neurol 2003;54:678–681

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