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Effect of ultrasound on thrombolysis of middle cerebral artery occlusion
Author(s) -
Eggers Jürgen,
Koch Björn,
Meyer Karsten,
König Inke,
Seidel Günter
Publication year - 2003
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.10590
Subject(s) - thrombolysis , medicine , middle cerebral artery , transcranial doppler , barthel index , occlusion , plasminogen activator , ultrasound , recombinant tissue plasminogen activator , stroke (engine) , artery , tissue plasminogen activator , doppler ultrasound , cardiology , anesthesia , surgery , ischemic stroke , radiology , ischemia , modified rankin scale , physical therapy , activities of daily living , mechanical engineering , myocardial infarction , engineering
We studied the effect of transcranial 2MHz Doppler ultrasound (US) on the recanalization and outcome of stroke patients suffering from acute middle cerebral artery occlusion. All patients underwent intravenous recombinant tissue‐type plasminogen activator thrombolysis. Eleven patients were randomly selected for continuous US monitoring (C‐US) over 1 hour; 14 patients were selected for the control group. The C‐US group showed a higher grade of recanalization after 1 hour but also a higher number of intraparenchymal bleedings. Overall, a favorable functional outcome occurred more frequently in the C‐US group (Barthel index, p = 0.037) after 3 months. Ann Neurol 2003;53:797–800