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Age‐dependent changes in the ability to encode a novel elementary motor memory
Author(s) -
Sawaki Lumy,
Yaseen Zaneb,
Kopylev Leonid,
Cohen Leonardo G.
Publication year - 2003
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.10529
Subject(s) - motor cortex , neuroscience , neuroplasticity , psychology , kinematics , plasticity , stroke (engine) , motor function , primary motor cortex , motor skill , motor system , motor activity , physical medicine and rehabilitation , medicine , mechanical engineering , physics , classical mechanics , stimulation , engineering , thermodynamics
In healthy individuals, motor training elicits cortical plasticity that encodes the kinematic details of the practiced movements and is thought to underlie recovery of function after stroke. The influence of age on this form of plasticity is incompletely understood. We studied 55 healthy subjects and identified a substantial decrease in training‐dependent plasticity as a function of age in the absence of differences in training kinematics. These results suggest that the ability of the healthy aging motor cortex to reorganize in response to training decreases with age. Ann Neurol 2003;53:521–524