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Imaging end points for monitoring neuroprotection in Parkinson's disease
Author(s) -
Brooks David J.
Publication year - 2003
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.10480
Subject(s) - neuroprotection , positron emission tomography , parkinson's disease , medicine , neuroscience , emission computed tomography , disease , degenerative disease , neuroimaging , psychology , pathology
In this review, the potential role of positron emission tomography and single‐photon emission computed tomography as biological markers for following the progression of Parkinson's disease (PD) is discussed, and their value for assessing the efficacy of putative neuroprotective agents in PD is considered. It is concluded that functional imaging provides a valuable adjunct to clinical assessment when judging the efficacy of neuroprotective approaches to PD. Ann Neurol 2003;53: (suppl 3)S110–S119