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Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis
Author(s) -
McDonald W. Ian,
Compston Alistair,
Edan Gilles,
Goodkin Donald,
Hartung HansPeter,
Lublin Fred D.,
McFarland Henry F.,
Paty Donald W.,
Polman Chris H.,
Reingold Stephen C.,
SandbergWollheim Magnhild,
Sibley William,
Thompson Alan,
Van Den Noort Stanley,
Weinshenker Brian Y.,
Wolinsky Jerry S.
Publication year - 2001
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.1032
Subject(s) - multiple sclerosis , medicine , magnetic resonance imaging , disease , mcdonald criteria , diagnostic test , pediatrics , radiology , pathology , psychiatry
Abstract The International Panel on MS Diagnosis presents revised diagnostic criteria for multiple sclerosis (MS). The focus remains on the objective demonstration of dissemination of lesions in both time and space. Magnetic resonance imaging is integrated with clinical and other paraclinical diagnostic methods. The revised criteria facilitate the diagnosis of MS in patients with a variety of presentations, including “monosymptomatic” disease suggestive of MS, disease with a typical relapsing‐remitting course, and disease with insidious progression, without clear attacks and remissions. Previously used terms such as “clinically definite” and “probable MS” are no longer recommended. The outcome of a diagnostic evaluation is either MS, “possible MS” (for those at risk for MS, but for whom diagnostic evaluation is equivocal), or “not MS.”