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Brain white matter anatomy of tumor patients evaluated with diffusion tensor imaging
Author(s) -
Mori Susumu,
Frederiksen Kim,
van Zijl Peter C. M.,
Stieltjes Bram,
Kraut Michael A.,
Solaiyappan Meiyappan,
Pomper Martin G.
Publication year - 2002
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.10137
Subject(s) - white matter , diffusion mri , inferior longitudinal fasciculus , superior longitudinal fasciculus , anatomy , tractography , corona radiata (embryology) , medicine , multislice , magnetic resonance imaging , astrocytoma , pathology , nuclear medicine , radiology , glioma , fractional anisotropy , cancer research , ovarian follicle , hormone , cumulus oophorus
We applied multislice, whole‐brain diffusion tensor imaging (DTI) to two patients with anaplastic astrocytoma. Data were analyzed using DTI‐based, color‐coded images and a 3‐D tract reconstruction technique for the study of altered white matter anatomy. Each tumor was near two major white matter tracts, namely, the superior longitudinal fasciculus and the corona radiata. Those tracts were identified using the color‐coded maps, and spatial relationships with the tumors were characterized. In one patient the tumor displaced adjacent white matter tracts, whereas in the other it infiltrated the superior longitudinal fasciclus without displacement of white matter. DTI provides new information regarding the detailed relationship between tumor growth and nearby white matter tracts, which may be useful for preoperative planning.