Open AccessPrediction of the neurological outcome using regional cerebral oxygen saturation in patients with extracorporeal cardiopulmonary resuscitation after out‐of‐hospital cardiac arrest: a multicenter retrospective cohort study
Author(s) -
Joo Woo Jin,
Ide Kazuki,
Nishiyama Kei,
Seki Tomotsugu,
Tanaka Hiroyuki,
Tsuchiya Jumpei,
Ito Noritoshi,
Yoshida Kosuke,
Kawakami Koji
Publication year - 2020
Publication title -
acute medicine and surgery
Language(s) - English
Resource type - Journals
ISSN - 2052-8817
DOI - 10.1002/ams2.491
Subject(s) - extracorporeal cardiopulmonary resuscitation , medicine , cardiopulmonary resuscitation , extracorporeal , retrospective cohort study , cardiology , receiver operating characteristic , cohort , emergency medicine , resuscitation
Aim To investigate the association between regional cerebral oxygen saturation (rSO2) and neurological outcomes in extracorporeal cardiopulmonary resuscitation (ECPR) patients after out‐of‐hospital cardiac arrest (OHCA). Methods We used data from the Japan‐Prediction of Neurological Outcomes in Patients Post‐Cardiac Arrest Registry. This registry included consecutive comatose patients after OHCA who were transferred to 15 hospitals in Japan from 2011 to 2013. Our primary end‐point was a good neurological outcome (cerebral performance categories 1 or 2) at 90 days after OHCA. Results Among the enrolled patients, 121 (6.3%) received ECPR. Eleven (9.1%) had a good neurological outcome. Receiver operating characteristic curve analysis revealed the optimal cut‐off value as >16%. Good neurological outcomes were observed in 19.6% (9/46) and 2.7% (2/74) of patients with rSO2 >16% and rSO2 ≤16%, respectively. Conclusion The neurological outcome of ECPR patients differed according to their rSO2 values. When considering ECPR, the rSO2 value could be important in addition to other criteria. Further studies that focus on ECPR patients and serial rSO2 values are needed.