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Oscillating flow bioreactors: An enabling technology for sustainable biorefining operations?
Author(s) -
MusterSlawitsch Bettina,
Buchmaier Judith,
Brunner Christoph,
Nidetzky Bernd,
Gudiminchi Rama K.,
Harvey Adam P.,
Phan Anh N.
Publication year - 2020
Publication title -
journal of advanced manufacturing and processing
Language(s) - English
Resource type - Journals
ISSN - 2637-403X
DOI - 10.1002/amp2.10046
Subject(s) - biorefining , bioreactor , process engineering , cellulose , biofuel , batch processing , continuous flow , sugar , pulp and paper industry , hydrolysis , process (computing) , flow (mathematics) , biochemical engineering , chemistry , computer science , environmental science , chemical engineering , waste management , biorefinery , engineering , mathematics , organic chemistry , operating system , geometry , programming language
In this work a novel reactor is evaluated on its potential to intensify biobased processing via a novel potentially continuous enzymatic hydrolysis process. An oscillatory flow bioreactor is applied in batch and recirculating mode, the latter mimicking the flow pattern of a continuous process. The recirculating mode operation can intensify cellulose conversion to hydrolyzed sugar liquid significantly, namely with enabling high solid processing and reaching >10% higher cellulose conversion than the respective operation in batch mode. Resulting sugar concentrations reach >90 mg/mL with the potential to enable the elimination of further concentration steps in down‐stream processing, having a positive impact on the overall efficiency and sustainability of further processing steps to biofuels or biochemicals.