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Actigraphic sleep patterns and cognitive decline in the Hispanic Community Health Study/Study of Latinos
Author(s) -
Agudelo Christian,
Tarraf Wassim,
Wu Benson,
Wallace Douglas M.,
Patel Sanjay R.,
Redline Susan,
Kaur Sonya,
Daviglus Martha,
Zee Phyllis C.,
Simonelli Guido,
MossavarRahmani Yasmin,
SotresAlvarez Daniela,
Zeng Donglin,
Gallo Linda C.,
González Hector M,
Ramos Alberto R.
Publication year - 2021
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1002/alz.12250
Subject(s) - actigraphy , cognitive decline , cognition , sleep onset latency , verbal fluency test , psychology , sleep (system call) , verbal learning , verbal memory , effects of sleep deprivation on cognitive performance , cohort , gerontology , medicine , audiology , dementia , sleep disorder , psychiatry , neuropsychology , insomnia , disease , pathology , computer science , operating system
We determined if actigraphy‐derived sleep patterns led to 7‐year cognitive decline in middle‐aged to older Hispanic/Latino adults. Methods We examined 1035 adults, 45 to 64 years of age, from the Hispanic Community Health Study/Study of Latinos. Participants had repeated measures of cognitive function 7 years apart, home sleep apnea studies, and 1 week of actigraphy. Survey linear regression evaluated prospective associations between sleep and cognitive change, adjusting for main covariates. Results Longer sleep‐onset latency was associated with declines in global cognitive function, verbal learning, and verbal memory. Longer sleep‐onset latency was also cross‐sectionally associated with verbal learning, verbal memory, and word fluency. Sleep fragmentation was not associated with cognitive change. Conclusion In a cohort of mostly middle‐aged Hispanic/Latinos, actigraphy‐derived sleep‐onset latency predicted 7‐year cognitive change. These findings may serve as targets for sleep interventions of cognitive decline.