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Shift work and incidence of dementia: A Danish Nurse Cohort study
Author(s) -
Jørgensen Jeanette Therming,
Hansen Johnni,
Westendorp Rudi G. J.,
NabeNielsen Kirsten,
Stayner Leslie Thomas,
Simonsen Mette Kildevæld,
Andersen Zorana Jovanovic
Publication year - 2020
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1002/alz.12126
Subject(s) - dementia , evening , danish , shift work , medicine , incidence (geometry) , hazard ratio , cohort study , cohort , night work , confidence interval , medical prescription , gerontology , demography , psychiatry , nursing , linguistics , philosophy , physics , disease , astronomy , sociology , optics
A few studies suggest that working night and rotating shifts increase the risk of dementia. We examined the association between shift work and the incidence of dementia in a cohort of female Danish nurses. Methods We linked Danish Nurse Cohort participants, who reported work schedules (day, evening, night, rotating shifts) in 1993 and/or 1999 and their duration in 2009, to Danish registers to obtain information on dementia hospitalizations and prescription medication until November 2018. Results Among 6048 nurses who reported work schedules in 1993 and 1999, nurses working night shifts ≥6 years had higher dementia incidence (hazard ratio: 2.43, 95% confidence interval: 1.39 to 4.23) than those working day shifts ≥6 years. Among 8059 nurses who reported shift work duration, nurses working night shifts ≥6 years had higher dementia incidence than those working night shifts <1 year (1.47, 1.06 to 2.06). Discussion Persistent night shift work may increase the risk of dementia.