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How many Black men in cognitive intervention trials? A persistent barrier to equity
Author(s) -
Forrester Sarah N,
Thorpe Roland J,
Hill Carl V,
Whitfield Keith E
Publication year - 2021
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1002/alz.052404
Subject(s) - cognition , medicine , psychological intervention , dementia , gerontology , cognitive decline , randomized controlled trial , cognitive intervention , clinical trial , intervention (counseling) , clinical psychology , psychiatry , disease
Background There has been sparse attention paid to the cognition of older men and potential race differences in cognitive ability among older men. Men’s health disparities are likely to continue to increase in the next few decades, likely due to an aging baby boom cohort; increases in racial diversity in the US; and increases in life expectancy among both Black and White men. Our objective was to examine the completed cognitive intervention trials to ascertain the proportion of Black men and racial differences in such trials. Method We conducted a scoping review of reported cognitive intervention trials between the years 2000 and 2020. We searched PubMed, Google Scholar, CINHAL, Cochrane, and Clinicaltrials.gov for cognitive intervention trials using the following MeSH terms – “cognitive intervention”, “mild cognitive impairment”, “dementia”, “Alzheimer’s disease”, and “cognitive disorder”. Inclusion criteria included U.S, based interventions intended to improve cognition. Result We found 293 unique trials that met our search terms of which 66 were included for final analysis. The rest were excluded due to not being in the US, only including healthy participants, and use of non‐cognitive interventions. We were able to assess the number of Black men in 9 out of the 66 trials, because the trials were either all White (n=8) or all Black (n=1). Of the 9 trials we could assess, 8 had no Black participants (thus no Black men) and the one with all Black participants had 21% men. Of the remaining 57 trials, 32 did not report race and 25 included race and sex data but did not include race‐sex categories and thus we were unable to determine the number of black men included. Conclusion We were unable to determine if cognitive intervention trials included sufficient proportions of Black men due to non‐reporting of race, race‐sex categories, and lack of inclusion of Black persons in trials. Our results beg the question of how we can understand cognitive health disparities and improve representation in trials if we don’t include the information that would allow us to make that determination.

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