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Potential drug interactions between hydroxychloroquine and anticholinesterase drugs
Author(s) -
Santos Gustavo AA
Publication year - 2020
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1002/alz.047692
Subject(s) - hydroxychloroquine , drug , medicine , disease , covid-19 , pandemic , intensive care medicine , pharmacology , infectious disease (medical specialty)
Background One of the main aggravating factors in the Covid‐19 pandemic is the lack of effective treatments capable of promoting a cure to date. Unfortunately, contrary to the recommendations of WHO and health authorities, in Brazil the use of Hydroxychloroquine in the treatment of SarsCov‐2 has been approved. Method We selected guidelines with recommendations for treatment of Covid 19, with an emphasis on the proposed treatments. Then we evaluate the main drug interactions and their potential risks. Result The risk of using Hydroxychloroquine in patients with Alzheimer's Disease is high, both due to the aspect of the disease itself, but also due to the drug interactions found. Conclusion Hydroxychloroquine is not recommended for patients with Alzheimer's Disease.