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AgeWell.de (Germany)
Author(s) -
Roehr Susanne,
Hoffmann Wolfgang,
Thyrian Jochen René,
Kaduszkiewicz Hanna,
Frese Thomas,
Gensichen Jochen,
Haefeli Walter E.,
Czock David,
König HansHelmut,
Wiese Birgitt,
RiedelHeller Steffi G.
Publication year - 2020
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1002/alz.046950
Subject(s) - dementia , intervention (counseling) , psychological intervention , medicine , randomized controlled trial , gerontology , population , cognition , cognitive decline , neuropsychology , clinical psychology , psychiatry , disease , environmental health , pathology , surgery
Background Based on the share of the population aged 65 years and older, Germany is among the world's oldest countries. Therefore, dementia prevention is a very important public health target. AgeWell.de is the first large‐scale multi‐component lifestyle intervention trial against cognitive decline in Germany. It has been designed with a specific focus on a pragmatic approach to allow easy translation into routine care. Method AgeWell.de is an ongoing multi‐centric, cluster‐randomized controlled multi‐component lifestyle intervention trial aiming at preventing or delaying cognitive decline. Participants are older community‐dwelling general practitioner (GP) patients (60–77 years; n > 1,000) with increased dementia risk according to the CAIDE (Cardiovascular Risk Factors, Aging, and Incidence of Dementia) dementia risk score. The multi‐component intervention A includes nutritional counseling, physical activity, cognitive training, optimization of medication, management of vascular risk factors, social activity, and, if necessary, further specific interventions targeting grief and depression. Intervention B includes general health advice regarding the intervention components and GP treatment as usual. The observation period is two years. Trained study nurses conduct structured interviews including a comprehensive neuropsychological test battery at baseline and follow‐ups, complemented by motivational telephone sessions with the intervention group. Results Recruitment and baseline assessments have been completed. Baseline characteristics of the study sample will be presented at AAIC. Conclusion AgeWell.de covers a broad set of lifestyle interventions. We therefore hope to add additional knowledge on how to effectively shape dementia prevention programs in the future.