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Subjective versus objective cognitive assessment in an ethnically diverse cohort of oldest‐old individuals: The LifeAfter90 Study
Author(s) -
Corrada Maria M.M.,
Kawas Claudia H.,
DeCarli Charles,
Gilsanz Paola,
Glymour M. Maria,
Mayeda Elizabeth Rose,
Mungas Dan M.,
Whitmer Rachel A.
Publication year - 2020
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1002/alz.046498
Subject(s) - cognition , episodic memory , cohort , psychology , neuropsychology , dementia , ethnic group , cognitive test , semantic memory , association (psychology) , cognitive decline , gerontology , medicine , psychiatry , disease , pathology , sociology , anthropology , psychotherapist
Background The ability to measure cognition accurately in ethnically diverse populations is important. However, information about cognition in the oldest‐old (people aged 90+) comes almost exclusively from cohorts of highly educated Caucasian individuals. We studied the association between self‐rated cognition and objectively measured cognition among the first 610 participants enrolled in an ongoing multi‐ethnic oldest‐old cohort. Method LifeAfter90 participants are long‐time members of the Kaiser Permanente Northern California Health Care System without a dementia diagnosis in their medical record at recruitment. Evaluations are every six months and include the Everyday Cognition (ECog) and Spanish and English Neuropsychological Assessment Scales (SENAS). The ECog is a self‐rated questionnaire about abilities to perform cognitively relevant functional tasks across multiple domains (on a 4‐point scale from ‘no change’ to ‘much worse’). For analysis, we averaged items within each domain (memory‐2, language‐2, visuospatial abilities‐5, and executive function‐7). The SENAS assesses episodic memory, semantic memory, and executive function domains. We estimated the cross‐sectional associations between self‐rated cognition (ECog) and objectively measured cognition (SENAS) measured at baseline. Using linear regression, we determined in the full cohort which ECog items had the strongest association with each SENAS domain and compared those associations across racial/ethnic groups. Result At baseline, participants were on average 92.6 years of age, 62% were women, 45% had a college education, and 68% were racial/ethnic minorities (Table 1). Table 2 shows the associations between ECog items and SENAS domains. ‘Concerned about memory’ was the ECog item most strongly associated with SENAS Verbal Memory, and that association was strongest among Whites and Blacks. The visuospatial ECog items had the strongest association with SENAS Semantic Memory, and that association was present among Whites and Latinos. The executive function ECog items had the strongest association with SENAS Executive Function, and the association was present among Whites and Latinos. No associations between ECog items and SENAS domains were observed among Asians or the multiracial group. Conclusion In this oldest‐old cohort, we found differences in how racial ethnic/groups report their everyday cognitive function in relation to their measured cognitive abilities. These differences need to be considered when assessing subjective cognitive function in diverse populations.