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Nativity differences in lifecourse socioeconomic position and late‐life cognition among KHANDLE participants
Author(s) -
Peterson Rachel,
George Kristen M,
Gilsanz Paola,
Mayeda Elizabeth Rose,
Glymour M Maria,
Mungas Dan M,
DeCarli Charles,
Whitmer Rachel A
Publication year - 2020
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1002/alz.045399
Subject(s) - socioeconomic status , cognition , cohort , ethnic group , psychology , gerontology , demography , neuropsychology , medicine , developmental psychology , population , psychiatry , sociology , anthropology
Background Socioeconomic position (SEP) in childhood and adulthood is associated with late‐life cognition. Less is known about how SEP changes may be associated with late‐life cognition in diverse cohorts. Methods The Kaiser Healthy Aging and Diverse Life Experiences Study (KHANDLE) is a cohort of community‐dwelling Kaiser Permanente members who reside in the San Francisco Bay area and Sacramento valley (n=1,708; Asians (24%), Blacks (26%), Latinos (20%) and Whites (30%)). KHANDLE aims to evaluate how lifecourse and sociocultural factors influence late‐life brain health and cognitive decline and contribute to race/ethnic disparities. We used linear regression to test the association between lifecourse SEP trajectories and late‐life cognition and tested if these associations differed by US vs. foreign nativity. Childhood SEP is a composite of parents’ education (≥HS vs.