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CAIDE risk score for the prediction of dementia risk in Mexican elders: 10/66 Dementia Research Group, population‐based study in Mexico
Author(s) -
SalinasContreras Rosa Maria,
AcostaCastillo Gilberto Isaac,
SosaOrtiz Ana Luisa
Publication year - 2020
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1002/alz.043409
Subject(s) - dementia , medicine , predictive value , cognitive impairment , body mass index , framingham risk score , population , gerontology , physical therapy , disease , environmental health
Background CAIDE (Cardiovascular Risk Factors, Aging, and dementia) Dementia Risk Score was developed to identify subjects with risk for developing dementia; using cardiovascular risk factors for dementia. CAIDE has showed to have a good predictive value. Mexican elders have different risk factors for dementia; the use of this type of score could be a good alternative to detect subjects at risk and implementing prevention strategies. Method We include 1,111 subjects of > 65 years of age, without cognitive impairment and who had the information complete to calculate CAIDE [age (< 47, 47‐53, >53 years old), gender, education (> 10 years, 7‐9 years, < 7 years), systolic blood pressure (<140 or >140mmHg), body mass index (<30 or >30 kg/m 2 ), the auto‐report of dyslipidaemia (the original CAIDE use only hypercholesterolemia) and physical activity. Diagnosis of dementia after the follow‐up was according to 10/66 algorithms, we determinate the predictive properties of CAIDE score. Result Those with a CAIDE score of 6‐7 showed a sensitivity of 66.23%, specificity of 34.7% and the 37.63% of proper classification at three years of follow‐up; for those with score of 8‐9, had a sensitivity 24.68%, specificity of 73.69% and the 69.18%, and for those with a score 10‐11, shown a sensitivity of 5.19%, specificity of 93.5% and the 85.4% of proper classification. Conclusion CAIDE score show a good specificity and sensibility. CAIDE scores of 6‐7 showed the best sensitivity but the 8‐9 scores obtain the best specificity. But we should consider different things for example we population have > 65 years old, this conditioning all our sample to obtain 4 points, and we use self‐report for some measures. CAIDE does not include diabetes, which has demonstrated to be an important risk factor for dementia in our population.