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Preliminary validation of the Brief Assessment of Impaired Cognition (BASIC) and the Brief Assessment of Impaired Cognition Questionnaire (BASIC‐Q) for identification of mild cognitive impairment
Author(s) -
Jørgensen Kasper,
Nielsen Rune,
Nielsen Ann,
Waldorff Frans Boch,
Waldemar Gunhild
Publication year - 2020
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1002/alz.042517
Subject(s) - cognition , psychology , dementia , cognitive assessment system , cognitive impairment , clinical psychology , discriminative model , developmental psychology , audiology , cognitive psychology , psychiatry , medicine , artificial intelligence , disease , pathology , computer science
Background The aim of this study was to perform a preliminary validation of the Brief Assessment of Impaired Cognition (BASIC) 1 and the Brief Assessment of Impaired Cognition Questionnaire (BASIC‐Q) 2 for identification of mild cognitive impairment (MCI). Method A total of 163 socio‐demographically matched patients (MCI, n = 42, and dementia, n = 121) and control participants (n = 83) were included in the study. BASIC includes the components: self‐report, informant report, and two brief cognitive tests, whereas BASIC‐Q includes the components: self‐report, informant report, and orientation. BASIC takes about 5 minutes to administer and BASIC‐Q a little less. Result A high discriminative validity for MCI versus control participants was found for both BASIC (sensitivity 0.85, specificity 0.89) and BASIC‐Q (sensitivity 0.88, specificity 0.88). In comparison, the MMSE had low sensitivity (0.61) and moderate specificity (0.72). All components of BASIC and BASIC‐Q contributed significantly to differentiate MCI from control participants. The components of BASIC and BASIC‐Q also contributed significantly to differentiate MCI from dementia except for self‐report, which was identical in the two groups. Conclusion The results indicate that BASIC and BASIC‐Q are equally efficient and valid instruments for identification of MCI in a memory clinic setting. Self‐report and informant report are equally valid measures of cognitive impairment early in the process of decline, but as dementia sets in the validity of self‐report becomes inferior to informant report, possibly reflecting loss of insight. In contrast, the validity of informant report seems to increase with the progression of cognitive impairment. Further studies are warranted to replicate and expand on these findings. References: 1. Jorgensen K, Nielsen TR, Nielsen A, Waldorff FB, Hogh P, Jakobsen S, et al. Brief Assessment of Impaired Cognition (BASIC)‐Validation of a new dementia case‐finding instrument integrating cognitive assessment with patient and informant report. Int J Geriatr Psychiatry. 2019;34(11):1724‐33. 2. Jorgensen K, Nielsen TR, Nielsen A, Waldorff FB, Waldemar G. Brief Assessment of Impaired Cognition Questionnaire (BASIC‐Q) – development and validation of a new tool for identification of cognitive impairment in community settings (submitted for publication). 2019.